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Hepatitis B Five Tests

Surface Antigen (HBsAg)
Surface Antibody (Anti-HBs)
e Antigen (HBeAg)
e Antibody (Anti-HBe)
Core Antibody (Anti-HBc)
Core Antibody (Anti-HBc) IgM

Interpretation

Test Item Test Value Clinical Significance
HBsAg
Anti-HBs
HBeAg
Anti-HBe
Anti-HBc
Negative
Negative
Negative
Negative
Negative
Susceptible
HBsAg
Anti-HBs
Anti-HBc
Negative
Positive
Positive
Previously infected with hepatitis B virus, now immune
HBsAg
Anti-HBs
Anti-HBc
Anti-HBc IgM
Positive
Negative
Positive
Positive
Acute infection
HBsAg
Anti-HBs
Anti-HBc
Anti-HBc IgM
Positive
Negative
Positive
Negative
Chronic infection
HBsAg
Anti-HBs
Anti-HBc
Negative
Negative
Positive
Unclear cause, possibly one of the following four situations:
1. Most commonly seen in recovered HBV infection
2. Anti-HBc false positive, susceptible
3. Low-level chronic infection
4. Acute infection recovery phase
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