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Physical Status Scoring Standards (KPS and ZPS Methods)

Karnofsky Scoring (KPS, Percentage Method) ECOG/WHO/Zubrod Score (ZPS, 5-Point Method)
Physical Condition Score (%) Physical Condition Score (Grade)
Normal, no symptoms or signs 100 Normal activity 0
Can perform normal activities, with mild symptoms or signs 90 Mild symptoms, comfortable life, can perform light physical activities 1
Can barely perform normal activities, with some symptoms or signs 80
Can take care of oneself, but cannot maintain normal work and life 70 Can tolerate tumor symptoms, can take care of oneself, but bedridden less than 50% of the day 2
Can mostly take care of oneself, but occasionally needs help 60
Often needs care 50 Severe tumor symptoms, bedridden more than 50% of the day, but can still get up and stand, partially self-sufficient 3
Cannot take care of oneself, needs special care and help 40
Severely unable to take care of oneself 30
Severely ill, needs hospitalization and active supportive treatment 20 Severely ill, bedridden 4
Critically ill, near death 10
Death 0 Death 5

Notes

Before treating tumor patients, their general health status should be evaluated. An important indicator of general health status is the evaluation of their performance status (PS). Performance status is an indicator of the patient's general health and tolerance to treatment based on their physical strength. The internationally used methods are the Karnofsky Performance Status (KPS) and the Zubrod Performance Status (ZPS) developed by the Eastern Cooperative Oncology Group (ECOG).

If the Karnofsky score is below 40%, the treatment response is often poor, and it is often difficult to tolerate chemotherapy reactions; ECOG has developed a simplified performance status scoring table, dividing the patient's performance status into 6 levels from 0 to 5. Generally, patients with performance status levels 3 and 4 are not suitable for chemotherapy.

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