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Back| Tumor Name | Cell Type | Secreted Hormone | Syndrome | Location |
|---|---|---|---|---|
| Insulinoma | β | Insulin | Hypoglycemia | Islets |
| Gastrinoma | G | Gastrin | Pancreatic Ulcer | Islets, Stomach, Duodenum |
| Glucagonoma | α | Glucagon | Diabetes, Necrolytic Migratory Erythema | Islets, occasionally Lung, Kidney |
| VIPoma | δ1 | Vasoactive Intestinal Peptide | Pancreatic Diarrhea | Islets, Neuroblastoma |
| Somatostatinoma | δ | Somatostatin | Inhibition Syndrome | Islets, Small Intestine |
| PPoma | PP | Pancreatic Polypeptide | Asymptomatic or Diarrhea | Islets |
| Neurotensinoma | NT | Neurotensin | Hypotension, Vasodilation, etc. | Pancreatic Sympathetic Chain |
| Carcinoid | EC | 5-Hydroxytryptamine | Carcinoid Syndrome | Islets, Digestive Tract |
Notes
There are many cells in the islets that have the function of secreting different hormones. Tumors developed from these cells are called pancreatic endocrine neoplasms (PEN). PENs are divided into two categories: one is functional tumors, named according to the main hormone they secrete (as shown in the table above); the other is non-functional islet cell tumors, which have normal serum hormone levels and no clinical symptoms.
