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Common Clinical Fluid Components and Tonicity

Solution Type Electrolyte Concentration (mmol/L) Electrolyte Osmolarity (Osm/L) Tonicity Remarks
Na+ K+ Cl- HCO3-
5% Glucose - - - - - - Commonly used to dilute electrolyte solutions
10% Glucose - - - - - - Commonly used to dilute electrolyte solutions
0.9% Sodium Chloride 154 154 308 Isotonic Not suitable for correcting metabolic acidosis
2:1 Solution (Isotonic Na Solution) 158 105 53 316 Isotonic Composed of 2 parts 0.9% NaCl and 1 part 1.4% NaHCO3, and 10% GS (no tonicity, used for dilution).
Modified Darrow's Solution (MD Solution) 117 40 104 53 314 Isotonic Can be given after urination
5% Sodium Bicarbonate 500 500 1000 Hypertonic Needs to be diluted 3 times to make isotonic solution
1/6 mol/L Sodium Lactate 167 167 334 Isotonic
1.4% Sodium Bicarbonate 167 167 334 Isotonic
Half-strength MD Solution 58.5 20 52 26.5 157 Hypotonic
Physiological Maintenance Solution 30 20 50 100 Hypotonic Maintains physiological water and electrolyte needs
Compound Electrolyte Glucose Injection (MG3) 50 20 50 20 140 Hypotonic
Oral Rehydration Salts (ORS) 90 20 80 30 220 Hypotonic Suitable for mild to moderate dehydration to replenish accumulated and ongoing losses
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