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Back| Diagnosis can be made if there is a fever of unknown origin lasting more than 5 days, along with 4 of the following 5 clinical manifestations after excluding other diseases: |
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| 1. Changes in peripheral limbs: acute palmoplantar erythema, hand-foot indurative edema; desquamation of fingertips and toes in the recovery phase. |
| 2. Polymorphic rash. |
| 3. Conjunctival injection, non-purulent. |
| 4. Lip congestion and cracking, diffuse congestion of oral mucosa, strawberry tongue appearance. |
| 5. Non-purulent cervical lymphadenopathy (approximately 1.5 cm in diameter). |
Explanation
Kawasaki Disease (KD), also known as mucocutaneous lymph node syndrome (MCLS), is an acute febrile rash disease characterized primarily by systemic inflammatory lesions of medium and small arteries.
The diagnosis of this disease is primarily based on clinical manifestations. Besides fever, having 4 of the 5 major manifestations listed above is sufficient for diagnosis. If only 3 or fewer of the major manifestations are present, an echocardiogram must confirm the presence of coronary artery dilation or aneurysm to establish a definitive diagnosis.
