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Common Medications for Neonatal Resuscitation in Asphyxia

Medication Concentration Preparation Amount Dosage Route and Speed Remarks
Adrenaline 1:10000 1ml 0.1~0.3ml/kg IV or IT rapid administration IT with NS 1:1
Sodium Bicarbonate 5% 10ml 2~3ml/kg IV slowly! 1.0ml/min Use only after effective ventilation, dilute to isotonic solution
Volume Expanders Own placental blood, whole blood, plasma, 5% human albumin, normal saline 40ml 10ml/kg IV over 15~30 min
Naloxone 0.4mg/mL
1mg/mL
1ml 0.1mg/kg IM, IV, IT or SC rapid administration
Dopamine
and/or
Dobutamine
6× body weight kg = mg of medication added to every 100ml GS Start at 5μg/kg·min (or half of each drug), increase to 20μg/kg·min if necessary IV infusion, strictly control drip rate Closely monitor heart rate and blood pressure

Instructions

Note: IT stands for intratracheal, SC stands for subcutaneous

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