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Diagnostic Criteria for Serum Thyroid Hormones in Congenital Hypothyroidism

Diagnosis Diagnostic Criteria
Primary Hypothyroidism TSH>9 mIU/L; FT4<0.6 ng/dL
Primary Subclinical Hypothyroidism TSH>9 mIU/L; FT4 normal (0.9-0.23 ng/dL)
TBG Deficiency TSH normal (<9 mIU/L); FT4 normal (0.9-0.23 ng/dL); TT4 decreased (<5μg/dL); T3RUR>45%
Central Hypothyroidism TSH<9 mIU/L or normal; FT4 decreased (<0.6ng/dL); TT4 decreased (<5μg/dL)

Explanation

T4: 1μg/dL*12.87=1nmol/L;

FT4: 1ng/dL*12.87=1pmol/L

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