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Score ≥2, high risk (annual stroke risk 4~18.2%), use warfarin anticoagulation therapy if no contraindications, maintain INR between 2-3;
Score = 1, moderate risk (annual stroke risk 2.8%), use warfarin or aspirin for anticoagulation therapy, depending on patient condition and physician's advice;
Score = 0, low risk (annual stroke risk 1.9%), recommend aspirin 325mg qd.
Recommended by ACC/AHA/ESC in 2006 for stroke risk stratification in atrial fibrillation patients, compared to CHA2DS2-VASc, it is clinically practical, simple, and easy to use.
1. Gage BF, et al. Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin. Circulation. 2004;110(16):2287-92.
2. Gage BF, et al. Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA. 2001;285(22):2864-70.
3. Go AS, et al. Anticoagulation therapy for stroke prevention in atrial fibrillation: how well do randomized trials translate into clinical practice? JAMA. 2003;290(20):2685-92.