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WHO-FC Pulmonary Hypertension Functional Classification

Class Description
Class I No limitation of usual physical activity. Ordinary physical activity does not cause undue dyspnea or fatigue, chest pain, or near syncope.
Class II Mild limitation of physical activity. No discomfort at rest, but ordinary physical activity causes undue dyspnea or fatigue, chest pain, or near syncope.
Class III Marked limitation of physical activity. No discomfort at rest, but less than ordinary activity causes undue dyspnea or fatigue, chest pain, or near syncope.
Class IV Inability to carry out any physical activity without symptoms. Signs of right heart failure. Dyspnea and/or fatigue may be present at rest, and discomfort is increased by any physical activity.

Description

Used for clinical symptom assessment of patients with pulmonary hypertension. For untreated idiopathic or hereditary pulmonary hypertension patients, the median survival time for WHO-FC Class IV is 6 months, for WHO-FC Class III is 2.5 years, and for WHO-FC Class I or II is 6 years.

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