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Sequential Organ Failure Assessment (SOFA) Score

Blood Pressure and Vasopressors
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Blood Pressure and Vasopressors
MAP>=70 mmHg
MAP<70 mmHg
Use of vasopressors, dopamine< 5 µg/kg/min or dobutamine (any dose)
Dopamine > 5 µg/kg/min or epinephrine/norepinephrine < 0.1 µg/kg/min
Dopamine > 15 µg/kg/min or epinephrine/norepinephrine > 0.1 µg/kg/min
Creatinine/24-hour Urine Output
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Creatinine
< 1.2 mg/dL (< 106 µmol/L)
1.2-1.9 mg/dL (106-168 µmol/L)
2.0-3.4 mg/dL (177-301 µmol/L)
3.5-4.9 mg/dL (309-433 µmol/L) or urine output<500ml
> 5.0 mg/dL (> 442 µmol/L) or urine output<200ml
Bilirubin (μmol/L)
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Bilirubin (μmol/L)
＜ 20
20-32
33-101
102-204
> 204
Platelet Count (×109/L)
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Platelet Count (×109/L)
> 149
100-149
50-99
20-49
< 20
Glasgow Coma Scale (GCS)
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Glasgow Coma Scale (GCS)
15
13-14
10-12
6-9
0-5
PaO₂ / FiO₂ Ratio (mmHg)
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PaO₂ / FiO₂ Ratio (mmHg)
>=400
300-399
200-299
100-199
<100
Score:

Explanation

The worst value of the day should be taken for daily assessment.

Result Interpretation

The SOFA scoring system has the advantages of being objective, simple, easy to collect data, able to dynamically observe the evolution of the disease, and facilitating the comparison of data from medical units in different regions. The results show that in ICU patients, the SOFA score at admission is not related to prognosis, while the maximum SOFA score and ΔSOFA score are very well correlated with prognosis. Among the correlation of each organ, the circulatory system has the best correlation with prognosis, followed by the kidneys and nervous system.

The SOFA score predicts mortality best in the first 48 hours of admission. If the SOFA score increases in the first 48 hours of admission, the predicted mortality rate is over 50%.

References

Research Paper 1. Sepsis-related Organ Failure (SOFA) Score. European Society of Intensive Care Medicine (ESICM), 1994. Research Paper 2. Vincent JL, Moreno R, Takala J, et al. The SOFA (sepsis-related organ failure assessment) score to describe organ dysfunction failure(J). Intensive Care Med, 1996, 22: 707-710.
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