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Chronic Myeloid Leukemia (CML) Sokal Score

Age
years
Spleen Size
cm
Platelet Count
109/L
Blast Cells
%
Sokal Score:

Calculation Formula

Sokal Score = exp([0.0116 × (Age – 43.4)] + [0.0345 × (Spleen Size – 7.51)] + [0.188 x ((Platelet Count / 700)2 – 0.563)] + [0.0887 × (Blast Cells – 2.10)])

Result Explanation

Score Risk Level 2-Year Survival Rate Median Survival
<0.8 Low Risk 90% 5 years
0.8-1.2 Intermediate Risk 65-90% 2.5-5 years
>1.2 High Risk 65% 2.5 years

References

Research Paper Sokal JE, Cox EB, Baccarani M, Tura S, Gomez GA, Robertson JE et al. Prognostic discrimination in “good-risk” chronic granulocytic leukemia. Blood 1984; 63: 789-99.
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