1. What is Corrected WBC for NRBC?

The corrected WBC count accounts for nucleated red blood cells (NRBCs) in peripheral blood samples. NRBCs are normally excluded from automated WBC counts, but when present in significant numbers, they can falsely elevate the WBC count.

2. How Does the Calculator Work?

The calculator uses the following formula:

Where:

• \( \text{Total WBC} \) — Initial white blood cell count (cells/μL)
• \( \text{NRBC} \) — Nucleated red blood cells per 100 white blood cells

Explanation: The formula adjusts the total WBC count by removing the falsely counted NRBCs that were included in the automated count.

3. Importance of Corrected WBC

Details: Correcting the WBC count is essential when NRBCs are present to avoid misdiagnosis of leukocytosis and ensure accurate interpretation of complete blood count results.

4. Using the Calculator

Tips: Enter the total WBC count from your lab report and the NRBC count per 100 WBCs. Both values must be positive numbers.

5. Frequently Asked Questions (FAQ)

Q1: When should I use this correction?
A: Use when NRBCs are reported in the differential count, typically when >0 NRBCs per 100 WBCs are present.

Q2: What is a normal NRBC count?
A: Normally, NRBCs are absent in peripheral blood of adults. Their presence may indicate hematologic disorders or stress responses.

Q3: How are NRBCs counted?
A: NRBCs are counted during manual differential counts and reported as number per 100 WBCs.

Q4: Does this correction affect other CBC parameters?
A: No, this correction only affects the WBC count. Other parameters like hemoglobin and platelets remain unchanged.

Q5: What conditions cause NRBCs in peripheral blood?
A: Conditions include hemolytic anemia, bone marrow infiltration, severe hypoxia, and hematologic malignancies.