Clotrimazole Data - Uses, Dosage, Drug class, Brand name, Warnings, etc

Pharmacology	Clotrimazole is an imidazole antifungal used for local therapy of fungal infections. Topical formulations are equivalent to other topical antifungals for Candida spp. and dermatophyte skin infections.
Adult Dosage	Topical for tinea infections: - Apply to affected area twice daily Vaginal Tablet for vulvovaginal candidiasis: - 100 mg at bedtime for 7 days - OR two 100 mg tablets at bedtime for 3 days - OR one 500 mg tablet once at bedtime Vaginal Cream for vulvovaginal candidiasis: - 1 applicatorful (50 mg) at bedtime for 6–14 days PO for oropharyngeal candidiasis treatment: - Dissolve 10 mg troche in mouth 5 times/day PO for prophylaxis of oral candidiasis in immunosuppressed patients: - Dissolve 10 mg troche in mouth 3 times/day
Pediatric Dosage	Topical: - Same as adult dosage Troche: - <3 yr: Safety and efficacy not established - ≥3 yr: Same as adult dosage Vaginal Cream/Tablet: - <12 yr: Safety and efficacy not established - ≥12 yr: Same as adult dosage
Dosage Forms	- Topical Cream, Lotion, Solution: 1% - Vaginal Cream: 1% - Troche: 10 mg - Vaginal Tablet: 100 mg, 500 mg Combination Packages: - Gyne-Lotrimin 3: Vaginal Suppository 200 mg (#3) + Vaginal Cream 1% - Gyne-Lotrimin 7: Vaginal Suppository 100 mg (#7) + Topical Cream 1%
Adverse Reactions	Troche: - Nausea, vomiting, bad taste, mildly abnormal liver function tests Vaginal Products: - Vulvovaginal burning, itching, irritation Topical/Vaginal: - Occasional skin rash

References

Hand of Clinical Drug Data