Griseofulvin Data - Uses, Dosage, Drug class, Brand name, Warnings, etc

Pharmacology	Griseofulvin is a fungistatic agent that disrupts mitosis in fungal cells. Active against dermatophytes; ineffective against yeasts or other fungal infections.
Adult Dosage	PO (microsize): - 0.5–1 g/day in a single dose or 2–4 divided doses PO (ultramicrosize): - 330–660 mg/day in 1–2 divided doses Duration: - General skin infections: ≥3 weeks - Palms/soles: 4–8 weeks - Nail infections: 6–12 months Take with meals to enhance absorption; avoid prolonged sun exposure and alcohol.
Pediatric Dosage	PO (microsize): - 11 mg/kg/day PO (ultramicrosize): - 7.3 mg/kg/day Administer as for adults (single or divided doses).
Dosage Forms	Microsize: - Capsule: 250 mg - Tablet: 250 mg, 500 mg - Suspension: 25 mg/mL Ultramicrosize: - Tablet: 125 mg, 165 mg, 250 mg, 330 mg
Adverse Reactions	Occasional: - Nausea, vomiting Rare: - Photosensitivity reactions, peripheral neuritis, leukopenia Other: - Can exacerbate acute intermittent porphyria